Research on Health Effects from Air Pollution
- Health Effects of Air Pollutants on Vulnerable Populations
- Long-Term and Short-Term Effects from Exposure to Air Pollutants
- Multipollutant Exposures and Changes in Environmental Conditions
- Leveraging Big Data for Innovations in Health Science
- Health Effects of Wildfire Smoke
- Public Health Intervention and Communications Strategies
- Integrated Science Assessments for Air Pollutants
Health Effects of Air Pollutants on Vulnerable Populations

Research has shown that some people are more susceptible than others to air pollutants. These groups include children, pregnant women, older adults, and individuals with pre-existing heart and lung disease. People in low socioeconomic neighborhoods and communities may be more vulnerable to air pollution because of many factors. Proximity to industrial sources of air pollution, underlying health problems, poor nutrition, stress, and other factors can contribute to increased health impacts in these communities.
There is a need for greater understanding of the factors that may influence whether a population or age group is at increased risk of health effects from air pollution. In addition, advances to analytical approaches used to study the health effects from air pollution will improve exposure estimates for healthy and at-risk groups.
The research by EPA scientists and others inform the required reviews of the primary National Ambient Air Quality Standards (NAAQS), which is done with the development of Integrated Science Assessments (ISAs). These ISAs are mandated by Congress every five years to assess the current state of the science on criteria air pollutants and determine if the standards provide adequate protection to public health.
Research is focused on addressing four areas:
- Identifying and characterizing whether there are key reproductive factors and critical stages of development that are impacted by air pollution exposures;
- Determining the role of acute and chronic sociodemographic factors in air pollution health disparities;
- Understanding how diet modifies responses to air pollution;
- Evaluating long-term lifestyle and chronic disease effects on air pollution-induced respiratory and cardiovascular responses
A multi-disciplinary team of investigators is coordinating epidemiological, human observational, and basic toxicological research to assess the effects of air pollution in at-risk populations and develop strategies to protect these populations, particularly those with pre-existing disease. The results from these products will improve risk assessments by clarifying the role of modifying factors such as psychosocial stress (e.g. noise) and diet, and determining the impact of individual susceptibility on the relationship between air pollutant exposures and health.
- Healthy Heart Research
- Integrated Science Assessments
- Criteria Air Pollutants
Health Effects of Air Pollutants on Vulnerable Populations

Larger and more intense wildfires are creating the potential for greater smoke production and chronic exposures in the United States, particularly in the West. Wildfires increase air pollution in surrounding areas and can affect regional air quality.
The health effects of wildfire smoke can range from eye and respiratory tract irritation to more serious disorders, including reduced lung function, exacerbation of asthma and heart failure, and premature death. Children, pregnant women, and the elderly are especially vulnerable to smoke exposure. Emissions from wildfires are known to cause increased visits to hospitals and clinics by those exposed to smoke.
It is important to more fully understand the human health effects associated with short- and long-term exposures to smoke from wildfires as well as prescribed fires, together referred to as wildland fires. EPA is conducting research to advance understanding of the health effects from different types of fires as well as combustion phases. Researchers want to know
- What is the full extent of health effects from smoke exposure?
- Who is most at risk?
- Are there differences in health effects from different wildfire fuel types or combustion phases (burning versus flaming)?
- What strategies and approaches are most effective in protecting public health?
- What are the environmental, social and economic impacts of wildfire emissions?